Dr.  Yuelin HE

Dr. Yuelin HE

  • Chief Physician
  • Deputy Director, GoBroad Chunfu Institute of Hematology & Oncology
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About the Doctor

Dr. Yuelin He has dedicated more than 30 years to pediatric hematology and hematopoietic stem cell transplantation (HSCT), and is recognized as one of China’s leading experts in this field. She is the recipient of the Tenth "Soong Ching Ling Pediatric Award" and a key contributor to the “Clinical Study on Allogeneic Hematopoietic Stem Cell Transplantation in the Treatment of Severe Mediterranean Anemia.”

Dr. He has independently or jointly completed over 1,200 HSCT procedures for children with severe thalassemia, various types of leukemia, lymphoma, aplastic anemia, congenital immunodeficiency disorders, autoimmune diseases, and other rare and complex hematologic conditions. She is particularly skilled in developing individualized transplantation strategies for high-risk, refractory, and relapsed cases, and excels in full-course management of critically ill pediatric patients.

She graduated from the First Military Medical University (now Southern Medical University), later trained at the Department of Pediatrics and Adolescent Medicine of Queen Mary Hospital, The University of Hong Kong, and has participated in collaborative HSCT research with leading centers in Italy and Japan. Dr. He has published more than 100 academic papers and has presented her work multiple times at major international meetings such as ASH and EHA, contributing significantly to the advancement and standardization of pediatric HSCT in China.

Areas of Expertise

  • HSCT for high-risk and refractory pediatric leukemia
  • Standardized transplantation for severe thalassemia and other hereditary blood disorders
  • HSCT for congenital immunodeficiency and autoimmune diseases
  • Comprehensive management of pediatric hematologic malignancies and complex blood diseases
  • Management of HSCT-related complications, including GVHD and severe infections

Contact information and location

Whatsapp
+86 15901185120
Address
Taixin Hospital,No.2 Taixin Road,Lixin Management District,Dongcheng District,Dongguan City,Guangdong,China

Related reading

Youzi (Age 3), China – Diamond-Blackfan Anemia (DBA)

At the end of February 2022, two life-changing events came to a young family almost simultaneously. While the new parents joyfully welcomed their newborn daughternicknamed Little Youzi (pseudonym)they were immediately confronted with heartbreaking news. From birth, Little Youzi appeared extremely pale. Repeated blood tests over several days showed persistent abnormalities, and doctors suspected an anemic disorder.

After a series of genetic tests and bone marrow examinations, she was ultimately diagnosed with congenital pure red cell aplasia, Diamond-Blackfan Anemia (DBA)a rare hereditary disorder of childhood characterized by failure of erythropoiesis, where the bone marrow cannot produce enough red blood cells to support normal growth and development.

Initial treatment with corticosteroids yielded poor results, and Little Youzi began regular blood transfusions. While transfusions could temporarily sustain her, they did not improve her condition. Her growth and development lagged significantly behind her peers, causing her parents deep concern.

In April 2024, the family sought help from Professor Chunfu Li, a renowned pediatric hematopoietic stem cell transplantation (HSCT) expert, had successfully treated multiple cases of DBA with transplantation. After thorough evaluation, Little Youzi underwent TDH transplantationa haploidentical allogeneic HSCT with T-cell depletion (ex vivo T-cell removal). This strategy not only addressed the lack of a fully matched donor but also reduced the risk of graft rejection.

Although she experienced adenovirus infection and gastrointestinal complications post-transplant, the medical teams expertise and attentive care guided her through the critical period. Gradually, her laboratory indices normalized, and she was discharged in stable condition. This milestone signified that her once paralyzed red cell factory had successfully restarted, enabling her to produce healthy red blood cells independently and freeing her from lifelong dependence on transfusionsmarking a victorious battle for survival.

 

Case Summary Little Youzi (3 years old)

Diagnosis: Congenital pure red cell aplasia Diamond-Blackfan Anemia (DBA)

l  2022: Diagnosed with DBA at 3 months of age; initiated steroid therapy and regular blood transfusions.

l  April 2024: First consultation at Chunfu Research Institute; pre-transplant evaluation completed.

l  June 2024: Admitted for transplantation; underwent TDH haploidentical allogeneic HSCT with ex vivo T-cell depletion.

l  August 2024: Discharged post-transplant; continued outpatient follow-up.

l  Now: One year post-transplant, recovering well and living at home.

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